Antibody Design Lab
25 famous monoclonal antibodies, from Trastuzumab to bispecifics and nanobodies. Edit CDRs, score developability, design variants — all in your browser.
Featured antibodies
What's inside
25 Famous Antibodies
Blockbusters like Trastuzumab, Pembrolizumab, and Adalimumab — plus bispecifics, ADCs, nanobodies, and COVID neutralizers.
CDR-Level Editor
Interactive heavy + light chain editor with CDR highlighting. Make single-point mutations in the CDR-H3 loop and see properties update instantly.
Developability Radar
Six-axis radar scoring solubility, viscosity, immunogenicity, aggregation, humanness, and thermostability — the real issues in antibody manufacturing.
Humanness Scoring
Heuristic germline identity against human V-region references. Understand immunogenicity risk without sending sequences to expensive SaaS tools.
Full Pipeline Studio
For full antigen-to-candidate workflows, the existing 7-step pipeline (fold → epitope → design → fold → complex → developability → rank) still lives at /discover/.
PubMed Literature
Every antibody links directly to a curated PubMed search. Read the primary literature from the same page where you're editing the sequence.
FAQ
Is this a clinical tool?›
No. Antibody Lab is an educational and research playground. It is not a diagnostic or clinical tool. FDA-approved antibodies are clearly labeled; research-only and EUA entries carry disclaimers.
Are the sequences real?›
Heavy and light chain sequences come from published literature, IMGT germline databases, and the Ab Engineer Database. Some canonical variable-region sequences use framework templates where primary publications are paywalled — we call those out in the history notes.
What does humanness mean?›
Humanness is the fraction of 4-mer substrings in your antibody that appear in human germline V-region references. High humanness predicts low immunogenicity. Our score is a heuristic, not a substitute for T-cell assays.
Can I design my own antibody?›
Yes. Every workspace has a heavy + light chain editor, and the /new page accepts custom sequences. Edit any CDR and watch molecular weight, pI, and the developability radar update in real time. Save designs to your account.
What about bispecifics and nanobodies?›
The library includes blinatumomab, teclistamab, mosunetuzumab (CD20×CD3), emicizumab (factor IX×X) bispecifics plus caplacizumab and ozoralizumab nanobodies. For nanobodies, the 'heavy chain' slot holds the VHH sequence and light chain is null.
Ready to design an antibody?
Open the lab, pick a famous antibody, and start editing.