DNA Lab
The first aggregator API for Evo 2 — the 9-trillion-basepair DNA foundation model with a 1-million-token context. Score variants, generate sequences, explore genome-scale biology in one API call.
What's inside
Evo 2 Variant Scoring
Zero-shot variant effect prediction on any DNA sequence. Score BRCA1 variants, find noncoding pathogenic mutations, evaluate synthetic CRISPR edits — all without fine-tuning.
9 Trillion Base Pair Training
Evo 2 was trained on a genomic atlas spanning all domains of life — bacteria, archaea, eukaryotes, viruses, and organelles. The 7B variant is API-accessible on our Pro tier.
1 Million Token Context
The longest context window in any biology model. Score variants with massive upstream and downstream context, generate genome-scale sequences, or process entire protein coding regions in one call.
The Hype Model of 2026
Evo 2 is the most-cited DNA foundation model of 2026. Arc Institute / Stanford built it, Nature published it, and SciRouter is the first aggregator API to host it alongside protein models.
FAQ
What is Evo 2?›
Evo 2 is a DNA foundation model developed by Arc Institute and Stanford. It has 7B and 40B parameter variants, trained on 9 trillion base pairs spanning all domains of life. It has a 1-million-token context window at single-nucleotide resolution and predicts variant effects zero-shot.
How does zero-shot variant scoring work?›
You provide a DNA sequence and a variant position + allele. Evo 2 computes the log-likelihood of the variant relative to the reference — negative scores indicate pathogenic variants, positive scores indicate benign. No training data or labels needed.
Can I use this to score my 23andMe variants?›
Yes — the /free/predict-your-variant tool uses Evo 2 to score protein-coding variants from uploaded 23andMe / AncestryDNA files. Parsing happens client-side; only the derived variant positions are sent to the API.
What about the 40B variant?›
The 40B variant requires multi-GPU A100 80GB and is available on our Pro tier. The 7B variant fits on a single A100 and is available on the free tier (up to 100 variants / month).
Is Evo 2 running live, or is this mock mode?›
Sprint 52 ships with deterministic mock mode while the RunPod worker is being provisioned. Every response includes a 'dispatch_mode' field (mock | runpod) so you always know which backend served your call.