API Reference

31 endpoints across 10 categories. All endpoints accept JSON and return JSON.

Authentication

All API requests require a Bearer token in the Authorization header.

curl https://scirouter.ai/v1/chemistry/properties \
  -H "Authorization: Bearer sk-sci-YOUR_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"smiles": "CCO"}'

Base URL

https://scirouter.ai

SDKs

Pythonpip install scirouter
TypeScriptnpm install @scirouter/sdk

Chemistry

3 endpoints

Molecular property calculation, format conversion, and similarity search.

POST/v1/chemistry/properties1 cr
POST/v1/chemistry/convert1 cr
POST/v1/chemistry/similarity1 cr

Proteins

3 endpoints

Protein structure prediction, embeddings, and function annotation.

POST/v1/proteins/fold10 cr
GET/v1/proteins/fold/{job_id}
POST/v1/proteins/embeddings5 cr

Docking

4 endpoints

Molecular docking and protein-ligand complex prediction.

POST/v1/docking/vina15 cr
POST/v1/docking/diffdock20 cr
POST/v1/complexes/chai125 cr
POST/v1/complexes/boltz225 cr

Design

3 endpoints

Protein sequence design, stability, and solubility prediction.

POST/v1/design/proteinmpnn10 cr
POST/v1/design/stability5 cr
POST/v1/design/solubility3 cr

Antibodies

2 endpoints

Antibody structure prediction and CDR sequence design.

POST/v1/antibodies/fold15 cr
POST/v1/antibodies/design15 cr

Generation

2 endpoints

Novel molecule generation and synthetic accessibility.

POST/v1/generate/molecules20 cr
POST/v1/generate/synthesis-check2 cr

Pharma

2 endpoints

ADME/Tox prediction for drug candidates.

POST/v1/pharma/adme3 cr
POST/v1/pharma/targets5 cr

Labs (Pipelines)

4 endpoints

End-to-end scientific workflows chaining multiple models.

POST/v1/labs/discover/evaluate50 cr
POST/v1/labs/engineer/optimize40 cr
POST/v1/labs/antibody/discover60 cr
POST/v1/labs/moldesign/generate80 cr

Interpret

2 endpoints

Plain-English interpretation and cross-model comparison.

POST/v1/interpret2 cr
POST/v1/interpret/compare3 cr

Platform

6 endpoints

API key management, usage tracking, and tool discovery.

POST/v1/keys
GET/v1/keys
DELETE/v1/keys/{key_id}
GET/v1/usage
GET/v1/tools
GET/health

Rate Limits

Free

10 req/min

Pro

60 req/min

Agentic

120 req/min

Enterprise

Custom