For Antibody Engineers

Design Therapeutic Antibodies — From Target to Candidate

Fold antibodies with ImmuneBuilder, design CDRs with AntiFold, score humanness and developability. The full pipeline in under 5 minutes. Free for researchers.

No install · No GPU · Free for .edu emails (750 credits/month)

The Antibody Design Pipeline

Four steps from sequence to developable therapeutic candidate.

1

Fold

Predict antibody 3D structure from VH + VL sequences

ImmuneBuilderAb-specific
~10s
ESMFold
~3s
2

Humanize

Score humanness against germline repertoire

Humanness Score
instant
AbLang2 Embeddings
~1s
3

Design CDRs

Generate optimized CDR sequences

AntiFoldCDR-aware
~10s
ProteinMPNN
~5s
4

Score

Predict developability and manufacturability

Developability
~1s
Physicochemical
instant

Frequently Asked Questions

Start designing antibodies today

Browse 25 famous therapeutic antibodies, score your own sequences, or run the full target-to-candidate pipeline. Free for researchers.