ProteinsCPU0 credits

Antibody Design Lab

Browse 25 famous antibodies, edit CDRs, score developability

A molecular playground for antibody engineers. Browse 25 curated antibodies (Trastuzumab, Pembrolizumab, Adalimumab, plus bispecifics, ADCs, and nanobodies), edit heavy and light chain CDRs with live highlighting, compute humanness against human germlines, and score six-axis developability including solubility, viscosity, immunogenicity, aggregation, and thermostability.

Free

per API call

credits per call

POST /v1/antibody-lab/calculate/properties

API endpoint

Features

25 famous antibodies: blockbusters + bispecifics + nanobodies + COVID neutralizers

Dual-chain editor with CDR highlighting (Kabat numbering)

Instant physicochemical recalc: MW, pI, extinction coefficient, GRAVY, instability

6-axis developability radar (solubility, viscosity, immunogenicity, aggregation, humanness, thermostability)

Heuristic germline humanness scoring against human V-region references

CDR-aware mutation suggester for single-point optimization

Save designs to your account with full developability snapshot

Existing 7-step antigen-to-candidate pipeline at /discover/ (ImmuneBuilder + AntiFold)

PubMed literature auto-linked for every antibody

FDA status badges and research-only disclaimers throughout

Quick Start

SciRouter Antibody Engine + ImmuneBuilder + AntiFold — Python Examplepython

import requests

# List the 25-antibody library
r = requests.get("https://scirouter.ai/v1/antibody-lab/antibodies")
print(r.json()["data"]["total"])  # 25

# Calculate properties for a heavy + light chain pair
response = requests.post(
    "https://scirouter.ai/v1/antibody-lab/calculate/properties",
    json={
        "heavy_chain": "EVQLVESGGGLVQPGGSLRLSCAAS...",  # Trastuzumab VH
        "light_chain": "DIQMTQSPSSLSASVGDRVTITCRAS..."   # Trastuzumab VL
    }
)
p = response.json()["data"]
print(f"MW: {p['molecular_weight']/1000:.1f} kDa")
print(f"pI: {p['isoelectric_point']:.2f}")

# Score humanness
h = requests.post(
    "https://scirouter.ai/v1/antibody-lab/humanness",
    json={"heavy_chain": "EVQLVESGGGLVQPGGSLRLSCAAS..."}
)
print(f"Humanness: {h.json()['data']['overall_humanness']:.2f}")