Synthetic BiologyCPU5 credits

Cello — Genetic Circuit Design

Design genetic circuits like logic chips

Cello is the MIT-developed CAD tool for synthetic biology — you write a truth table, it picks gates from a library, and out comes a DNA sequence that implements the logic in a living cell. SciRouter exposes Cello (plus SynBioHub parts registry and DeepCRISPR guide scoring) as one synthetic biology API.

$0.05
per API call
5
credits per call
/v1/synbio/design-circuit
API endpoint

Features

Truth-table → DNA sequence
SynBioHub parts library
Dynamic range + leakiness prediction
SBOL export

Quick Start

Cello + SynBioHub — Python Examplepython
import requests

r = requests.post(
    "https://scirouter-gateway-production.up.railway.app/v1/synbio/design-circuit",
    headers={"Authorization": "Bearer sk-sci-..."},
    json={
        "logic": "AND",
        "inputs": ["IPTG", "aTc"],
        "output": "GFP",
        "chassis": "E.coli",
    },
)
result = r.json()["data"]
print(f"Parts: {len(result['parts'])}")
print(f"Dynamic range: {result['dynamic_range']:.1f}x")

Use Cases

1

Biosensor design

2

Metabolic pathway switches

3

Teaching synthetic biology

4

iGEM competitions

Learn More

Genetic Circuit Design API: Cello and CRISPR Guide RNA Scoring

13 min read

Start Using Cello

500 free credits every month. No credit card required.

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