GenomicsGPU8 credits

Evo 2 — DNA Foundation Model

Zero-shot DNA variant effect prediction with 1M token context

Evo 2 is a 7B / 40B parameter DNA foundation model from Arc Institute and Stanford. Trained on 9 trillion base pairs across all domains of life, with a 1-million-token context window at single-nucleotide resolution. Predicts variant pathogenicity zero-shot — no fine-tuning required.

$0.08

per API call

credits per call

/v1/dna/evo2/variant-score

API endpoint

Features

Zero-shot variant effect prediction

9 trillion base pair training data

1 million token context window

Log-likelihood scoring for pathogenicity

Also supports DNA sequence generation

Quick Start

Evo 2 — Python Examplepython

import requests

# Score a variant
result = requests.post(
    "https://scirouter.ai/v1/dna/evo2/variant-score",
    json={
        "sequence": "ATCG...",
        "variant_position": 1234,
        "variant_allele": "T",
    },
    headers={"Authorization": "Bearer sk-sci-your-key"}
).json()["data"]
print(f"Variant score: {result['variant_score']}")
print(f"Interpretation: {result['interpretation']}")