DesignCPU2 credits

NetSolP — Solubility Prediction

Predict protein soluble expression probability

NetSolP predicts the probability of soluble recombinant protein expression in E. coli directly from amino acid sequence. Essential for prioritizing constructs in high-throughput cloning and expression campaigns.

$0.02

per API call

credits per call

/v1/design/solubility

API endpoint

Features

Solubility probability prediction from sequence

E. coli expression system optimized

No structure required — sequence only

Fast CPU inference

Batch processing support

Soluble vs insoluble classification

Quick Start

NetSolP — Python Examplepython

import requests

API_KEY = "sk-sci-your-key-here"
url = "https://scirouter.ai/v1/design/solubility"

response = requests.post(url, json={
    "sequence": "MKFLILLFNILCLFPVLAADNHGVS..."
}, headers={"Authorization": f"Bearer {API_KEY}"})

result = response.json()
print(f"Solubility probability: {result['solubility_probability']:.3f}")
print(f"Classification: {result['classification']}")