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Canine cancer, in plain English.

Calm, accurate explainers for owners. What the diagnosis means, what symptoms to watch for, what diagnosis and treatment look like at the vet, what questions to ask. We don't diagnose your dog — that's your veterinarian's job — but we can help you walk into the next appointment less lost.

15 of the most common cancers in dogs.

Each article walks you through what the cancer is, what to watch for, how vets typically diagnose and treat it, what questions to ask, and where to look for clinical trials.

Appendicular osteosarcoma

Bone cancer in a leg — the most common bone cancer in dogs.

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Multicentric lymphoma

Cancer of lymphocytes in multiple lymph nodes — the most common canine lymphoma.

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Splenic hemangiosarcoma

Aggressive cancer of blood-vessel-lining cells, usually in the spleen.

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Mast cell tumors in dogs

The most common skin cancer in dogs. Behavior ranges from easily curable to aggressively metastatic — grade and stage drive everything.

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Oral melanoma in dogs

The most common malignant oral tumor in dogs. Aggressive locally, and prone to spreading to lymph nodes and lungs — early detection makes a real difference.

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Cutaneous (skin) hemangiosarcoma in dogs

A skin-only form of hemangiosarcoma. When caught while it's still confined to the skin, it's far more treatable than its splenic cousin.

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Axial osteosarcoma in dogs

Osteosarcoma of the skull, jaw, spine, ribs, or pelvis — the less common but locally trickier sibling of the limb form. Surgical accessibility drives the treatment plan.

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Soft tissue sarcoma in dogs

A group of related tumors that arise from connective tissues — fat, muscle, nerve sheaths, fibrous tissue. They tend to grow locally, recur if undertreated, but metastasize less than many other cancers.

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Histiocytic sarcoma in dogs

An aggressive cancer of histiocyte-lineage immune cells. Bernese Mountain Dogs are dramatically over-represented but any breed can be affected — early intervention matters.

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Transitional cell carcinoma (bladder cancer) in dogs

The most common canine bladder cancer. Often presents like a stubborn UTI — and recurring UTI-like signs in a middle-aged or older dog deserve a closer look.

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Anal sac adenocarcinoma in dogs

A locally invasive tumor of the apocrine glands of the anal sacs. Often found by your vet on a routine rectal exam — and can cause unusual systemic signs through high blood calcium.

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Thyroid carcinoma in dogs

Most canine thyroid tumors are carcinomas — and most are biologically aggressive, in contrast to the predominantly benign thyroid tumors common in cats.

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Mammary tumors in dogs

About half of mammary tumors in intact female dogs are malignant. Early spay before the first heat dramatically reduces lifetime risk — but for diagnosed tumors today, prompt surgery is the priority.

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Squamous cell carcinoma in dogs

A keratinocyte-derived cancer most commonly seen in the oral cavity, on the digits (toenail beds), or on sun-exposed skin. Location drives treatment.

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Nasal tumors in dogs

Tumors of the nasal cavity — most often adenocarcinoma, chondrosarcoma, or squamous cell carcinoma. Locally destructive but slow to metastasize. Radiation is the workhorse therapy.

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How we write

Calm, accurate, never alarmist.

Articles are written for pet parents — not for veterinarians, not for journalists, not for investors. We use plain English, name what's uncertain, and end every piece with a reminder to talk to your vet.

All articles are educational only. They cite peer-reviewed veterinary literature where relevant. As we sign clinical-review partnerships with board-certified veterinary oncologists, each article will carry that reviewer's name and credentials visibly at the top.